| CAS No.: | 1415456-99-3 |
|---|---|
| Formula: | C187h291n45o59 |
| EINECS: | 203-405-2 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Refined |
| Customization: |
|---|
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Product Information
Product Name: Cagrilintide
CAS No.: 1415456-99-3
Purity: >99.0%
Molecular Formula: C187H291N45O59
Molecular Weight: 4409g/mol
Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(C18diacid-γ-Glu-OEG-OEG)]-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH
Appearance: White Lyophilized powder
Reconstitution: Required
Storage:After reconstitution store at 2°C - 8°C
Description:
Cagrilintide is under development for the treatment of obesity and type 2 diabetes. The drug candidate is administered as a once-daily and once-weekly subcutaneous formulation. It is a long-acting amylin analogue. Amylin is co-located with insu in secretory granules and co-secreted with insu by pancreatic beta cells in response to food intake.
CagriSema is a combination medication of the GLP-1 receptor agonist semaglutide and cagrilintide. Cagrilinitide mimics the hormone amylin, which is produced by the pancreas. Together with insu, amylin makes people feel satiated or full after eating a meal.
CagriSema is a once-weekly injection of semaglutide and cagrilintide. Phase 2 clinical trial results for CagriSema showed significant improvements in A1C, weight loss, and time in range, marking it as a promising new type 2 diabetes treatment.
|
Measure |
CagriSema |
Semaglutide |
Cagrilinitide |
|
Number of participants |
31 |
31 |
30 |
|
Average decrease in A1C |
2.2% |
1.8% |
0.9% |
|
Percentage of participants with an A1C ≤ 6.5% |
75% |
48% |
17% |
|
Average decrease in body weight |
15.6% |
5.1% |
8.1% |
|
Average increase in time in range |
43% | 43.6% | 14.8% |
Service:
1. Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.
Advantages:
1. Faster delivery: Sample order in stock and 3-7 days for bulk production.
2. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
3. After-Sale Service:
1) International Authorized Third-Party Test For The Products You Demand.
2) 60 Days Warranty of quality of goods.
Q1: What is your MOQ?
A: The minimum quantity we can order is 1 box.
But usually we can accept a smaller quantity, say 100g, at the cost of 100% sample charge.
Q2: How to start orders or make payments?
A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union, Money Gram.
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1.You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples.
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T/T, Western Union PayPal, and BTC. This is negotiable.
Q5: How do you treat quality complaint?
Our quality control will reduce the quality problem to near zero. If there is a real
quality problem caused by us, we will send you free goods for replacement.
Q6: Time for delivery?
Leading time within 3 business days,Shipping time about 8-10 business days.
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